Woman taking medicine

Admira Dentistry’s approach to care is grounded in beauty, health, and balance, with a clear understanding that oral health plays a direct role in overall wellness. Led by Dr. Julio Sixto, DMD, whose advanced training includes the Las Vegas Institute for Advanced Dental Studies, the American Academy of Cosmetic Dentistry, and the American Academy of Facial Esthetics, our team routinely evaluates how systemic factors, including prescription medications, impact the health of the gums. Medication-related gum overgrowth is a clinically recognized condition we see regularly, and when left unaddressed, it can compromise oral health, comfort, and confidence. Here’s what you need to know about why it occurs and how it is managed.

What Is Medication-Induced Gum Overgrowth

Medication-induced gum overgrowth, also known as gingival enlargement, occurs when certain prescription medications trigger excessive growth of gum tissue. Instead of maintaining a firm, natural contour around the teeth, the gums may thicken and expand, sometimes covering portions of the tooth surface. As the tissue enlarges, it becomes more difficult to clean effectively, increasing the likelihood of inflammation, infection, and periodontal disease.

This condition is most often associated with specific categories of medications, including some anti-seizure drugs such as phenytoin, immunosuppressive medications commonly prescribed after organ transplantation, and calcium channel blockers used to manage high blood pressure. Individual response varies, and factors such as genetics, existing gum health, and daily oral hygiene habits all influence the severity of the overgrowth.

Why Certain Medications Affect the Gums

Certain medications alter normal cellular activity within the gum tissues, particularly the way connective tissue cells grow and break down. Gum tissue is especially susceptible to these changes because it is constantly exposed to mechanical stress, bacteria, and inflammation along the tooth margin.

When plaque is present, the medication-related tissue response can become more pronounced, accelerating enlargement and creating deeper gum pockets. Over time, these pockets trap bacteria and are difficult to clean, increasing the risk of infection, periodontal disease, and damage to the structures that support the teeth. The visible impact of enlarged gums can also affect smile aesthetics and self-confidence.

Signs You Should Not Ignore

Gum overgrowth typically develops gradually, making regular dental evaluations essential for early detection. Patients often first notice subtle changes that progress over time. Signs that warrant professional evaluation include:

  • Enlarged gum tissue: Gums appear thicker than usual or extend farther over the teeth.
  • Bleeding or tenderness: Gums bleed easily during brushing or feel persistently sore.
  • Changes in daily hygiene: Brushing and flossing become more difficult due to excess tissue or tight spaces.

Addressing these signs early allows for more conservative treatment and helps prevent long-term periodontal complications.

How Gum Overgrowth Is Managed

Managing medication-related gum overgrowth requires an individualized, medically informed approach. Patients should never discontinue or adjust prescribed medications without direction from the prescribing physician. Dental treatment instead focuses on controlling inflammation and addressing contributing factors.

Care at Admira Dentistry often begins with professional cleanings and personalized guidance to improve daily oral hygiene. When appropriate, we collaborate with a patient’s medical provider to discuss whether alternative medications may be considered. If gum enlargement persists despite these measures or begins to interfere with oral health, function, or appearance, advanced periodontal therapy or precise tissue reshaping may be recommended to restore healthy contours.

Protecting Your Smile Long Term

Medication-induced gum overgrowth highlights the strong connection between oral and systemic health. With regular dental evaluations and timely periodontal care, medication-related gum changes can often be managed before they affect comfort or function. At Admira Dentistry, Dr. Sixto and our team take a personalized, evidence-based approach to identifying these concerns early and guiding patients toward long-term oral wellness. If your medications are impacting your gums, scheduling a consultation allows us to evaluate your needs and develop an appropriate care plan.


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